If you change media_processing.conf you'll have to reprocess all existing images to see a difference. You may consider changing the viewer used for PDFs in media_display.conf to PDF.js. This will use the PDF directly, and generally provides significantly better quality. The configuration would look something like this:
pdf = {
mimetypes = {application/pdf},
display_version = tilepic,
alt_display_version = mediumlarge,
width = 100%, height = 100%,
download_version = original,
# Scroll mode to open viewer with by default. Values are:
# VERTICAL = vertical scrolling
# HORIZONTAL = horizontal scrolling
# WRAPPED = wrapped display
# DEFAULT = user default (whatever the user last selected)
scroll_mode = DEFAULT,
viewer = pdfjs
},